About ReadingFrame
An independent publication for readers who want a closer look at the papers.
ReadingFrame is an independent research publication at reading-frame.com. We explain science research in short breakdowns that connect the finding to the evidence behind it.
Our approach
Our coverage connects clear explanations to primary sources, with careful attention to what the evidence supports. We welcome questions and corrections from readers.
What ReadingFrame covers
Our coverage includes bioinformatics, cancer genomics, gene editing, drug discovery, computational methods, neuroscience, immunology, protein design, clinical research, ecology, and materials science. Each breakdown focuses on a research paper or development and links to its sources. You can browse the research breakdowns by topic or start with the latest post.
How to read a breakdown
Start with the finding section, then read the evidence section for the experimental details. We keep the study setting and comparisons beside each finding so a result from a simulation or a laboratory experiment is not mistaken for a demonstrated benefit in people. A preprint and a peer-reviewed paper carry different levels of review; neither removes the need to examine the evidence.
Why the name ReadingFrame?
In biology, a reading frame determines how a nucleotide sequence is divided into codons. The name reflects the importance of context: understanding a research result means reading its headline in the context of its methods and assumptions.
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Corrections and questions
If you spot an error, contact ReadingFrame with a source for the passage you are asking about. You can also suggest a paper or ask about a method. To receive new breakdowns, join the ReadingFrame daily digest. When a correction changes a breakdown after publication, the post's byline shows an updated date alongside the original publish date.